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DNAJB11 Polyclonal Antibody

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Antibody Testing Data (9)

DNAJB11 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 9

DNAJB11 Antibody (15484-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using DNAJB11 antibody 15484-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

DNAJB11 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DNAJB11 Antibody in Immunoprecipitation (IP)

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Product Details

15484-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 15 publications 15 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DNAJB11 Fusion Protein Ag7832 (23-358 aa encoded by BC001144)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.18 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: GRDFYKILG VPRSASIKDI KKAYRKLALQ LHPDRNPDDP QAQEKFQDLG AAYEVLSDSE KRKQYDTYGE EGLKDGHQSS HGDIFSHFFG DFGFMFGGTP RQQDRNIPRG SDIIVDLEVT LEEVYAGNFV EVVRNKPVAR QAPGKRKCNC RQEMRTTQLG PGRFQMTQEV VCDECPNVKL VNEERTLEVE IEPGVRDGME YPFIGEGEPH VDGEPGDLRF RIKVVKHPIF ERRGDDLYTN VTISLVESLV GFEMDITHLD GHKVHISRDK ITRPGAKLWK KGEGLPNFDN NNIKGSLIIT FDVDFPKEQL TEEAREGIKQ LLKQGSVQKV YNGLQGY (23-358 aa encoded by BC001144)

Target Information

DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity bystimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus a glycine/phenylalanine (G/F)-rich region and a C-terminal cysteine-rich region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.

ACS chemical biology

Lyu Z,Sycks MM,Espinoza MF,Nguyen KK,Montoya MR,Galapate CM,Mei L,Genereux JC

Fri Jul 15 00:00:00 EDT 2022

Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.

Cellular & molecular biology letters

Liu P,Zu F,Chen H,Yin X,Tan X

Sat Oct 08 00:00:00 EDT 2022

The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.

Science (New York, N.Y.)

McKenna MJ,Sim SI,Ordureau A,Wei L,Harper JW,Shao S,Park E

Fri Sep 25 00:00:00 EDT 2020

Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network.

Molecular cell

Vonk WIM,Rainbolt TK,Dolan PT,Webb AE,Brunet A,Frydman J

Thu Apr 16 00:00:00 EDT 2020

Role of IRE1α in podocyte proteostasis and mitochondrial health.

Cell death discovery

Navarro-Betancourt JR,Papillon J,Guillemette J,Iwawaki T,Chung CF,Cybulsky AV

Thu Nov 19 00:00:00 EST 2020

Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease.

Laboratory investigation; a journal of technical methods and pathology

Tousson-Abouelazm N,Papillon J,Guillemette J,Cybulsky AV

Wed Jul 01 00:00:00 EDT 2020

Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.

Cell chemical biology

Plate L,Rius B,Nguyen B,Genereux JC,Kelly JW,Wiseman RL

Thu Jul 18 00:00:00 EDT 2019

PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress.

Scientific reports

Romine IC,Wiseman RL

Wed Jan 23 00:00:00 EST 2019

Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α₁-antitrypsin disposal.

The Journal of biological chemistry

Khodayari N,Oshins R,Alli AA,Tuna KM,Holliday LS,Krotova K,Brantly M

Fri Apr 19 00:00:00 EDT 2019

Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α₁-antitrypsin disposal.

The Journal of biological chemistry

Khodayari N,Oshins R,Alli AA,Tuna KM,Holliday LS,Krotova K,Brantly M

Fri Apr 19 00:00:00 EDT 2019

Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

He P,Tian N

Wed May 01 00:00:00 EDT 2019

Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.

Frontiers in immunology

Gómez-Fernández P,Urtasun A,Paton AW,Paton JC,Borrego F,Dersh D,Argon Y,Alloza I,Vandenbroeck K

Mon Oct 21 00:00:00 EDT 2019

Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response.

Frontiers in immunology

Gómez-Fernández P,Urtasun A,Paton AW,Paton JC,Borrego F,Dersh D,Argon Y,Alloza I,Vandenbroeck K

Mon Oct 21 00:00:00 EDT 2019

Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.

Cell death & disease

Osaki Y,Saito A,Kanemoto S,Kaneko M,Matsuhisa K,Asada R,Masaki T,Orii K,Fukao T,Tomatsu S,Imaizumi K

Tue Jul 24 00:00:00 EDT 2018

Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.

Cell death & disease

Osaki Y,Saito A,Kanemoto S,Kaneko M,Matsuhisa K,Asada R,Masaki T,Orii K,Fukao T,Tomatsu S,Imaizumi K

Tue Jul 24 00:00:00 EDT 2018

Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.

Journal of cellular biochemistry

Khodayari N,Marek G,Lu Y,Krotova K,Wang RL,Brantly M

Sun Oct 01 00:00:00 EDT 2017

Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.

Journal of cellular biochemistry

Khodayari N,Marek G,Lu Y,Krotova K,Wang RL,Brantly M

Sun Oct 01 00:00:00 EDT 2017

Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.

Journal of cellular biochemistry

Khodayari N,Marek G,Lu Y,Krotova K,Wang RL,Brantly M

Sun Oct 01 00:00:00 EDT 2017

Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.

Journal of cellular biochemistry

Khodayari N,Marek G,Lu Y,Krotova K,Wang RL,Brantly M

Sun Oct 01 00:00:00 EDT 2017

Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection.

Cell

Taguwa S,Maringer K,Li X,Bernal-Rubio D,Rauch JN,Gestwicki JE,Andino R,Fernandez-Sesma A,Frydman J

Thu Nov 19 00:00:00 EST 2015

Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection.

Cell

Taguwa S,Maringer K,Li X,Bernal-Rubio D,Rauch JN,Gestwicki JE,Andino R,Fernandez-Sesma A,Frydman J

Thu Nov 19 00:00:00 EST 2015

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.

The EMBO journal

Genereux JC,Qu S,Zhou M,Ryno LM,Wang S,Shoulders MD,Kaufman RJ,Lasmézas CI,Kelly JW,Wiseman RL

Fri Jan 02 00:00:00 EST 2015

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.

The EMBO journal

Genereux JC,Qu S,Zhou M,Ryno LM,Wang S,Shoulders MD,Kaufman RJ,Lasmézas CI,Kelly JW,Wiseman RL

Fri Jan 02 00:00:00 EST 2015

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.

The EMBO journal

Genereux JC,Qu S,Zhou M,Ryno LM,Wang S,Shoulders MD,Kaufman RJ,Lasmézas CI,Kelly JW,Wiseman RL

Fri Jan 02 00:00:00 EST 2015

Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.

The EMBO journal

Genereux JC,Qu S,Zhou M,Ryno LM,Wang S,Shoulders MD,Kaufman RJ,Lasmézas CI,Kelly JW,Wiseman RL

Fri Jan 02 00:00:00 EST 2015

A high-throughput cell-based Gaussia luciferase reporter assay for identifying modulators of fibulin-3 secretion.

Journal of biomolecular screening

Hulleman JD,Brown SJ,Rosen H,Kelly JW

Mon Jul 01 00:00:00 EDT 2013

A high-throughput cell-based Gaussia luciferase reporter assay for identifying modulators of fibulin-3 secretion.

Journal of biomolecular screening

Hulleman JD,Brown SJ,Rosen H,Kelly JW

Mon Jul 01 00:00:00 EDT 2013

Bioinformatics

Protein Aliases: ABBP-2; APOBEC1-binding protein 2; DnaJ (Hsp40) homolog, subfamily B, member 11; DnaJ homolog subfamily B member 11; DnaJ protein 9; DnaJ protein homolog 9; Endoplasmic reticulum DNA J domain-containing protein 3; ER-associated DNAJ; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; ER-resident protein ERdj3; ERdj3; ERj3p; hDj-9; HEDJ; Human DnaJ protein 9; Liver regeneration-related protein LRRGT00084; PWP1-interacting protein 4

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Gene Aliases: 1810031F23Rik; ABBP-2; ABBP2; AL024055; Dj-9; DJ9; DNAJB11; EDJ; ERdj3; ERJ3; ERj3p; HDJ9; LRRGT00084; PRO1080; PSEC0121; UNQ537; UNQ537/PRO1080

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UniProt ID: (Human) Q9UBS4, (Mouse) Q99KV1, (Rat) Q6TUG0

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Entrez Gene ID: (Human) 51726, (Mouse) 67838, (Rat) 360734

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Function(s)

protein binding unfolded protein binding chaperone

Process(es)

protein folding mRNA modification positive regulation of ATPase activity IRE1-mediated unfolded protein response

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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DNAJB11 Polyclonal Antibody

DNAJB11 Antibody (15484-1-AP) in ICC/IF

Product Details

15484-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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