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Invitrogen
DNAJB6 Polyclonal Antibody
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Product Details
PA5-121060
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 177-326 of human DNAJB6 (NP_490647.1).
Conjugate
Form
Liquid
Concentration
0.96 mg/mL
Amount
96 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: SW480, MCF7, 293T, Jurkat, HeLa, Mouse testis, Mouse brain, Rat brain. The target is usually found in the following locations: Cytoplasm, Nucleus, Z line, myofibril, perinuclear region, sarcomere.
Immunogen sequence: STSFGGSGMG NFKSISTSTK MVNGRKITTK RIVENGQERV EVEEDGQLKS LTINGVADDD ALAEERMRRG QNALPAQPAG LRPPKPPRPA SLLRHAPHCL SEEEGEQDRP RAPGPWDPLA SAAGLKEGGK RKKQKQREES KKKKSTKGNH
Target Information
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chaperon; DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ homolog subfamily B member 6; DnaJ-like 2 protein; DNAJB6; dnajb6 {ECO:0000312|EMBL:AAH78908.1, ECO:0000312|RGD:1308207}; Heat shock protein J2; HHDJ1; HSJ-2; Hsp40 homolog; mammalian relative of DnaJ; mDj4; MRJ; MSJ-1; unnamed protein product
Gene Aliases: DJ4; DnaJ; DNAJB6; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; LGMDD1; mDj4; MRJ; MSJ-1; MSJ1
UniProt ID: (Human) O75190, (Mouse) O54946, (Rat) Q6AYU3
Entrez Gene ID: (Human) 10049, (Mouse) 23950, (Rat) 362293
protein folding
actin cytoskeleton organization
extracellular matrix organization
positive regulation of ATPase activity
protein localization to nucleus
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
intermediate filament organization
negative regulation of transcription, DNA-templated
chorio-allantoic fusion
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
chorion development
chaperone-mediated protein folding
negative regulation of inclusion body assembly
regulation of protein localization
neurological system process
regulation of cellular response to heat
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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