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OriGene
DNAJB6 Monoclonal Antibody (OTI2F10), TrueMAB™
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FIGURE: 1 / 2
DNAJB6 Antibody (CF810656) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DNAJB6 (RC201620, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-DNAJB. Positive lysates LY417262 (100 µg) and LC417262 (20 µg) can be purchased separately from OriGene.
Product Details
CF810656
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2F10
Immunogen
Full length human recombinant protein of human DNAJB6 produced in HEK293T.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chaperon; DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ homolog subfamily B member 6; DnaJ-like 2 protein; DNAJB6; dnajb6 {ECO:0000312|EMBL:AAH78908.1, ECO:0000312|RGD:1308207}; Heat shock protein J2; HHDJ1; HSJ-2; Hsp40 homolog; mammalian relative of DnaJ; mDj4; MRJ; MSJ-1; unnamed protein product
Gene Aliases: DJ4; DnaJ; DNAJB6; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; LGMDD1; mDj4; MRJ; MSJ-1; MSJ1
UniProt ID: (Human) O75190, (Mouse) O54946, (Rat) Q6AYU3
Entrez Gene ID: (Human) 10049, (Mouse) 23950, (Rat) 362293
protein folding
actin cytoskeleton organization
extracellular matrix organization
positive regulation of ATPase activity
protein localization to nucleus
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
intermediate filament organization
negative regulation of transcription, DNA-templated
chorio-allantoic fusion
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
chorion development
chaperone-mediated protein folding
negative regulation of inclusion body assembly
regulation of protein localization
neurological system process
regulation of cellular response to heat
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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