Proteintech

DNAJC10 Polyclonal Antibody

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DNAJC10 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 13101-1-AP (DNAJC10 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

DNAJC10 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human pancreas cancer using 13101-1-AP (DNAJC10 antibody) at dilution of 1:100 (under 10x lens).

DNAJC10 Antibody in Western Blot (WB) — Mouse liver tissue were subjected to SDS PAGE followed by western blot with 13101-1-AP (DNAJC10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Product Details

13101-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 12 publications 12 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DNAJC10 Fusion Protein Ag3737 (690-793 aa encoded by BC034713)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

The ERdj5 antibody displays a higher affinity for endogenous ERdj5u.

Immunogen sequence: HWVIDFYAP WCGPCQNFAP EFELLARMIK GKVKAGKVDC QAYAQTCQKA GIRAYPTVKF YFYERAKRNF QEEQINTRDA KAIAALISEK LETLRNQGKR NKDEL (690-793 aa encoded by BC034713)

Target Information

This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. DNAJC10 may act as a co-chaperone for HSPA5.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin.

Cancers

Alalem M,Bhosale M,Ranjan A,Yamamoto S,Kaida A,Nishikawa S,Parrales A,Farooki S,Anant S,Padhye S,Iwakuma T

Mon Aug 29 00:00:00 EDT 2022

Thyroglobulin Interactome Profiling Defines Altered Proteostasis Topology Associated With Thyroid Dyshormonogenesis.

Molecular & cellular proteomics : MCP

Wright MT,Kouba L,Plate L

Mon Mar 14 00:00:00 EDT 2022

DNAJC10 correlates with tumor immune characteristics and predicts the prognosis of glioma patients.

Bioscience reports

Liu F,Tu Z,Liu J,Long X,Xiao B,Fang H,Huang K,Zhu X

Fri Jan 28 00:00:00 EST 2022

DNAJC10 correlates with tumor immune characteristics and predicts the prognosis of glioma patients.

Bioscience reports

Liu F,Tu Z,Liu J,Long X,Xiao B,Fang H,Huang K,Zhu X

Fri Jan 28 00:00:00 EST 2022

Hydrogen sulfide accumulates LDL receptor precursor via downregulating PCSK9 in HepG2 cells.

American journal of physiology. Cell physiology

Huang Y,Ning K,Li WW,Lin G,Hou CL,Wang MJ,Zhu YC

Tue Dec 01 00:00:00 EST 2020

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.

Diabetes

Tran DT,Pottekat A,Mir SA,Loguercio S,Jang I,Campos AR,Scully KM,Lahmy R,Liu M,Arvan P,Balch WE,Kaufman RJ,Itkin-Ansari P

Sat Aug 01 00:00:00 EDT 2020

Downregulation of DNAJC10 (ERDJ5) is associated with poor survival in breast cancer.

Breast cancer (Tokyo, Japan)

Acun T,Senses KM

Fri May 01 00:00:00 EDT 2020

Regulation of growth hormone biosynthesis by Cdk5 regulatory subunit associated protein 1-like 1 (CDKAL1) in pituitary adenomas.

Endocrine journal

Takesue Y,Wei FY,Fukuda H,Tanoue Y,Yamamoto T,Chujo T,Shinojima N,Yano S,Morioka M,Mukasa A,Kuratsu J,Tomizawa K

Sat Sep 28 00:00:00 EDT 2019

Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.

Cell stress & chaperones

Montibeller L,de Belleroche J

Sat Sep 01 00:00:00 EDT 2018

Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.

Cell stress & chaperones

Montibeller L,de Belleroche J

Sat Sep 01 00:00:00 EDT 2018

Mapping wild-type and R345W fibulin-3 intracellular interactomes.

Experimental eye research

Hulleman JD,Genereux JC,Nguyen A

Thu Dec 01 00:00:00 EST 2016

Mapping wild-type and R345W fibulin-3 intracellular interactomes.

Experimental eye research

Hulleman JD,Genereux JC,Nguyen A

Thu Dec 01 00:00:00 EST 2016

A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum.

PLoS pathogens

Walczak CP,Ravindran MS,Inoue T,Tsai B

Sat Mar 01 00:00:00 EST 2014

A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum.

PLoS pathogens

Walczak CP,Ravindran MS,Inoue T,Tsai B

Sat Mar 01 00:00:00 EST 2014

The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation.

Molecular biology of the cell

Williams JM,Inoue T,Banks L,Tsai B

Fri Mar 01 00:00:00 EST 2013

The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation.

Molecular biology of the cell

Williams JM,Inoue T,Banks L,Tsai B

Fri Mar 01 00:00:00 EST 2013

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

International endodontic journal

Diamanti E,Mathieu S,Jeanneau C,Kitraki E,Panopoulos P,Spyrou G,About I

Fri Feb 01 00:00:00 EST 2013

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

International endodontic journal

Diamanti E,Mathieu S,Jeanneau C,Kitraki E,Panopoulos P,Spyrou G,About I

Fri Feb 01 00:00:00 EST 2013

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

International endodontic journal

Diamanti E,Mathieu S,Jeanneau C,Kitraki E,Panopoulos P,Spyrou G,About I

Fri Feb 01 00:00:00 EST 2013

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

International endodontic journal

Diamanti E,Mathieu S,Jeanneau C,Kitraki E,Panopoulos P,Spyrou G,About I

Fri Feb 01 00:00:00 EST 2013

Bioinformatics

Protein Aliases: DnaJ (Hsp40) homolog, subfamily C, member 10; DnaJ homolog subfamily C member 10; Endoplasmic reticulum DNA J domain-containing protein 5; Endoplasmic reticulum DnaJ-PDI fusion protein 1; ER-resident protein ERdj5; J domain-containing PDI-like protein; J domain-containing protein disulfide isomerase-like protein; J-domain-containing protein disulfide isomerase-like protein; Macrothioredoxin; MTHr; protein disulfide isomerase family A, member 19

Gene Aliases: 1200006L06Rik; D2Ertd706e; DNAJC10; ERDJ5; JPDI; MTHr; PDIA19; UNQ495/PRO1012

UniProt ID: (Human) Q8IXB1, (Rat) Q498R3, (Mouse) Q9DC23

Entrez Gene ID: (Human) 54431, (Rat) 295690, (Mouse) 66861

Molecular Function: chaperone