Proteintech

DNAJC10 Polyclonal Antibody

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DNAJC10 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 13101-1-AP (DNAJC10 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

DNAJC10 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human pancreas cancer using 13101-1-AP (DNAJC10 antibody) at dilution of 1:100 (under 10x lens).

DNAJC10 Antibody in Western Blot (WB) — Mouse liver tissue were subjected to SDS PAGE followed by western blot with 13101-1-AP (DNAJC10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Product Details

13101-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:3,000	View 5 publications 5 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:500	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	DNAJC10 Fusion Protein Ag3737 (690-793 aa encoded by BC034713) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.28 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

The ERdj5 antibody displays a higher affinity for endogenous ERdj5u.

Immunogen sequence: HWVIDFYAP WCGPCQNFAP EFELLARMIK GKVKAGKVDC QAYAQTCQKA GIRAYPTVKF YFYERAKRNF QEEQINTRDA KAIAALISEK LETLRNQGKR NKDEL (690-793 aa encoded by BC034713)

Target Information

This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. DNAJC10 may act as a co-chaperone for HSPA5.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.

Cell stress & chaperones

Montibeller L,de Belleroche J

Sat Sep 01 00:00:00 EDT 2018

Mapping wild-type and R345W fibulin-3 intracellular interactomes.

Experimental eye research

Hulleman JD,Genereux JC,Nguyen A

Thu Dec 01 00:00:00 EST 2016

A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum.

PLoS pathogens

Walczak CP,Ravindran MS,Inoue T,Tsai B

Sat Mar 01 00:00:00 EST 2014

The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocation.

Molecular biology of the cell

Williams JM,Inoue T,Banks L,Tsai B

Fri Mar 01 00:00:00 EST 2013

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

International endodontic journal

Diamanti E,Mathieu S,Jeanneau C,Kitraki E,Panopoulos P,Spyrou G,About I

Fri Feb 01 00:00:00 EST 2013

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

International endodontic journal

Diamanti E,Mathieu S,Jeanneau C,Kitraki E,Panopoulos P,Spyrou G,About I

Fri Feb 01 00:00:00 EST 2013

Bioinformatics

Protein Aliases: DnaJ (Hsp40) homolog, subfamily C, member 10; DnaJ homolog subfamily C member 10; Endoplasmic reticulum DNA J domain-containing protein 5; Endoplasmic reticulum DnaJ-PDI fusion protein 1; ER-resident protein ERdj5; J domain-containing PDI-like protein; J domain-containing protein disulfide isomerase-like protein; J-domain-containing protein disulfide isomerase-like protein; Macrothioredoxin; MTHr; protein disulfide isomerase family A, member 19

Gene Aliases: 1200006L06Rik; D2Ertd706e; DNAJC10; ERDJ5; JPDI; MTHr; PDIA19; UNQ495/PRO1012

UniProt ID: (Human) Q8IXB1, (Rat) Q498R3, (Mouse) Q9DC23

Entrez Gene ID: (Human) 54431, (Rat) 295690, (Mouse) 66861

Molecular Function: chaperone