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Product Details
PA5-83547
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DNAJC3. Recombinant protein control fragment (Product #RP-97910).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2790700
Product Specific Information
Immunogen sequence: VEKHLELGKK LLAAGQLADA LSQFHAAVDG DPDNYIAYYR RATVFLAMGK SKAALPDLTK VIQLKMDFTA ARLQRGHLLL KQGKLDEAED D
Target Information
This gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon-induced, dsRNA-activated protein kinase (PKR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DnaJ (Hsp40) homolog, subfamily C, member 3; DnaJ homolog subfamily C member 3; Endoplasmic reticulum DNA J domain-containing protein 6; ER-resident protein ERdj6; FLJ21288; Interferon-induced, double-stranded RNA-activated protein kinase inhibitor; Protein kinase inhibitor of 58 kDa; Protein kinase inhibitor p58; protein-kinase, interferon-inducible double stranded RNA dependent inhibitor
Gene Aliases: ACPHD; DNAJC3; ERdj6; HP58; P58; P58IPK; PRKRI
UniProt ID: (Human) Q13217
Entrez Gene ID: (Human) 5611
positive regulation of translation initiation in response to endoplasmic reticulum stress
IRE1-mediated unfolded protein response
negative regulation of apoptotic process
proteolysis involved in cellular protein catabolic process
defense response to virus
cellular response to cold
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of cyclin-dependent protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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