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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • DOC2A Antibodies

          Proteintech

          DOC2A Polyclonal Antibody

          View all (7) DOC2A antibodies

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          Cite DOC2A Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          DOC2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          DOC2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 3

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          DOC2A Antibody (20575-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20575-1-AP (DOC2A antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          DOC2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          DOC2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          DOC2A Antibody in Western Blot (WB)

          Product Details

          20575-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Target Information

          There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Doc2; Doc2-alpha; double C2, alpha; Double C2-like domain-containing protein alpha; double C2-like domains, alpha

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          Gene Aliases: Doc2; DOC2A

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          UniProt ID: (Human) Q14183, (Rat) P70611, (Mouse) Q7TNF0

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          Entrez Gene ID: (Human) 8448, (Rat) 65031, (Mouse) 13446

          View more View less

          Function(s)
          calcium ion binding protein binding calcium-dependent phospholipid binding syntaxin binding clathrin binding transporter activity
          Process(es)
          synaptic vesicle exocytosis regulation of calcium ion-dependent exocytosis vesicle fusion chemical synaptic transmission nervous system development calcium ion-regulated exocytosis of neurotransmitter exocytosis
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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