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Product Details
BS-12431R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DOCK2, amino acids 451-550.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 1% BSA
Contains
0.09% sodium azide
Storage conditions
-20°C
Target Information
The DOCK2 gene encodes a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dedicator of cyto-kinesis 2; Dedicator of cytokinesis protein 2; FLJ46592; Protein Hch
Gene Aliases: AI662014; AW122239; CED-5; DOCK2; Hch; IMD40; KIAA0209; MBC
UniProt ID: (Human) Q92608, (Mouse) Q8C3J5
Entrez Gene ID: (Human) 1794, (Rat) 360509, (Mouse) 94176
Molecular Function:
guanyl-nucleotide exchange factor
membrane raft polarization
establishment of T cell polarity
immunological synapse formation
myeloid dendritic cell activation involved in immune response
chemotaxis
small GTPase mediated signal transduction
actin cytoskeleton organization
positive regulation of GTPase activity
macropinocytosis
positive thymic T cell selection
negative thymic T cell selection
alpha-beta T cell proliferation
regulation of defense response to virus by virus
positive regulation of phagocytosis
cytoskeleton organization
T cell proliferation
T cell activation
alpha-beta T cell activation
positive regulation of Rac protein signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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