DOCK9 is a guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression of DOCK9 induces filopodia formation.
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Protein Aliases: Cdc42 guanine nucleotide exchange factor zizimin-1; Dedicator of cytokinesis protein 9; Zizimin-1
Gene Aliases: AA959601; AW538057; B230309H04Rik; D14Wsu89e; DOCK9; KIAA1058; mKIAA1058; ZIZ1; ZIZIMIN1
UniProt ID: (Human) Q9BZ29
Molecular Function: guanyl-nucleotide exchange factor