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Invitrogen
DOG-1 Polyclonal Antibody
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Product Details
PA5-86889
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to residues in Human ANO1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
DOG-1, the novel marker, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of kit or PDGFR alpha mutation status.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ano1; anoctamin 1, calcium activated chloride channel; Anoctamin-1; AT5G45830; ATDOG1; Ca2+-activated Cl- channel; cacium activated chloride channel; calcium activated chloride channel; DELAY OF GERMINATION 1; Discovered on gastrointestinal stromal tumors protein 1; FLJ10261; GAAS5; germination ability after storage 5; GLUCOSE SENSING QTL 5; GSQ5; K15I22.3; K15I22_3; membrane protein; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); Tumor-amplified and overexpressed sequence 2; unnamed protein product
Gene Aliases: ANO1; DOG1; INDMS; MYMY7; ORAOV2; TAOS2; TMEM16A
UniProt ID: (Human) Q5XXA6, (Mouse) Q6P5C6
Entrez Gene ID: (Human) 55107, (Mouse) 101772, (Rat) 309135
receptor binding
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
voltage-gated chloride channel activity
chloride channel activity
protein binding
iodide transmembrane transporter activity
identical protein binding
protein homodimerization activity
metal ion binding
protein dimerization activity
phospholipid scramblase activity
protein heterodimerization activity
transport
ion transport
cation transport
chloride transport
multicellular organism development
regulation of membrane potential
trachea development
cation transmembrane transport
chloride transmembrane transport
phospholipase C-activating G-protein coupled receptor signaling pathway
iodide transport
ion transmembrane transport
cellular response to heat
detection of temperature stimulus involved in sensory perception of pain
mucus secretion
protein localization to membrane
glial cell projection elongation
cellular response to peptide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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