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Bioss
DOK5 Polyclonal Antibody
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FIGURE: 1 / 2
DOK5 Antibody (BS-8587R) in Flow
Human HepG2 cells probed with Rabbit Anti-DOK5 Polyclonal Antibody (bs-8587R) at 1:50 for 40 minutes followed by incubation with Goat Anti-Rabbit IgG FITC Conjugated secondary (bs-0295G-FITC) at 1:100 (green) for 40 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).
Product Details
BS-8587R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DOK5/IRS6, amino acids 21-120.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; MGC16926; Protein dok-5
Gene Aliases: 2700055C10Rik; C20orf180; DOK5; IRS-6; IRS6; RGD1562846
UniProt ID: (Human) Q5TE53, (Mouse) Q91ZM9
Entrez Gene ID: (Human) 55816, (Mouse) 76829, (Rat) 502694
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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