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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated, cprresponding to A(9) N G E L K V F I D Q N L S P G K G(27) C of human DP1.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-20318 detects DP1 in human and mouse samples.
PA1-20318 has been successfully used in immunofluorescence, immunoprecipitation and Western blot procedures.
The PA1-20318 immunogen is a Synthetic peptide, KLH conjugated, cprresponding to A(9) N G E L K V F I D Q N L S P G K G(27) C of human DP1.
DP family contains at least two members, DP1 and 2. Structurally, DP1 and 2 are relatively conserved, yet their expression appears to be tissue specific. E2F 1, a functional target for the tumor suppressor protein Rb, heterodimerizes with DP1 and forms an active E2F transcriptional complex. The interaction between members of the E2F and the DP families is mediated, in part, by a leucine repeat which is weakly conserved between the two families.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cell cycle regulatory transcription factor DP1; DRTF1-polypeptide 1; E2F dimerization partner 1; E2F-related transcription factor; transcription factor Dp-1
Dp-1; DP1; DRTF1; RP11-230F18.1