Invitrogen

DPM1 Polyclonal Antibody

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DPM1 Antibody in Western Blot (WB) — Western Blot staining of Rat Liver lysate using Product # PA5-19028 at a concentration of 0.05 µg/mL, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.

Product Details

PA5-19028

Applications	Tested Dilution	Publications
Western Blot (WB)	0.1-0.3 µg/mL	-

Product Specifications
Species Reactivity	Rat
Host/Isotype	Goat / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide sequence (PQGRSSRQDKYS) corresponding to the N-terminus amino acids of Dpm1
Conjugate	Unconjugated
Form	Liquid
Concentration	0.5 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	TBS, pH 7.3, with 0.5% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_10983454

Product Specific Information

This antibody is predicted to react with mouse based on sequence homology.

Target Information

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: dolichol-phosphate (beta-D) mannosyltransferase 1; dolichol-phosphate mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase 1; OTTMUSP00000017164; RP23-391M18.1

Entrez Gene ID: (Rat) 296394

Molecular Function: glycosyltransferase transferase metabolite interconversion enzyme