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This antibody is predicted to react with mouse based on sequence homology.
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dolichol-phosphate (beta-D) mannosyltransferase 1; dolichol-phosphate mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase 1; OTTMUSP00000017164; RP23-391M18.1
Entrez Gene ID: (Rat) 296394
Molecular Function:
glycosyltransferase
transferase
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