This antibody has been tested in Western blot applications using transfected lysates only.
Suggested positive control: antigen standard for DPP10 (transient overexpression lysate).
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dipeptidyl peptidase 10; Dipeptidyl peptidase IV-related protein 3; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; dipeptidyl-peptidase 10 (inactive); dipeptidyl-peptidase 10 (non-functional); DPL2; DPP X; DPRP-3; HGNC:20823; Inactive dipeptidyl peptidase 10; OTTHUMP00000203618
Gene Aliases: DPL2; DPP10; DPPY; DPRP-3; DPRP3; KIAA1492
UniProt ID: (Human) Q8N608
Entrez Gene ID: (Human) 57628
Molecular Function: serine protease