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Invitrogen
DPP3 Polyclonal Antibody
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FIGURE: 1 / 1
DPP3 Antibody (PA5-89210) in WB
Western blot analysis of DPP3 in extracts of various cell lines. Samples were incubated with DPP3 Polyclonal antibody (Product # PA5-89210) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-89210
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DPP3 (NP_5697102)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Amount
29 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MADTQYILPN DIGVSSLDCR EAFRLLSPTE RLYAYHLSRA AWYGGLAVLL QTSPEAPYIY ALLSRLFRAQ DPDQLRQHAL AEGLTEEEYQ AFLVYAAGVY SNMGNYKSFG DTKFVPNLPK EKLERVILGS EAAQQHPEEV RGLWQTCGEL MFSLEPRLRH LGLGKEGITT YFSGNCTMED AKLAQDFLDS QNLSAYNTRL FKEVDGEGKP YYEVRLASVL GSEPSLDSEV TSKLKSYEFR GSPFQVTRGD YAPILQKVVE QLEKAKAYAA NSHQGQMLAQ; Positive Samples: BT-474, HT-29, SKOV3, MCF-7, Mouse liver, Rat liver, Rat brain; Cellular Location: Cytoplasm
Target Information
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase 3; Dipeptidyl peptidase III; dipeptidyl-peptidase 3; dipeptidyl-peptidase III; dipeptidylpeptidase III; DPP III; Enkephalinase B; hCG_2016942; unnamed protein product
Gene Aliases: 4930533O14Rik; C86324; DPP3; DPPIII
UniProt ID: (Human) Q9NY33, (Rat) O55096, (Mouse) Q99KK7
Entrez Gene ID: (Human) 10072, (Rat) 114591, (Mouse) 75221
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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