Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
DPYD Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-79168
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human DPYD (33-52aa AKKLDKKHWKRNPDKNCFNC).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: MM231 Cell.
Target Information
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DHPDHase; Dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase; DPD
Gene Aliases: AI315208; DHP; DHPDHASE; DPD; DPYD; E330028L06Rik
UniProt ID: (Human) Q12882, (Rat) O89000, (Mouse) Q8CHR6
Entrez Gene ID: (Human) 1806, (Rat) 81656, (Mouse) 99586
protein binding
dihydropyrimidine dehydrogenase (NADP+) activity
protein homodimerization activity
metal ion binding
flavin adenine dinucleotide binding
NADP binding
4 iron, 4 sulfur cluster binding
uracil binding
dihydroorotate dehydrogenase activity
iron-sulfur cluster binding
nucleotide binding
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
purine nucleobase catabolic process
pyrimidine nucleobase catabolic process
thymine catabolic process
uracil catabolic process
thymidine catabolic process
beta-alanine biosynthetic process
pyrimidine nucleoside catabolic process
oxidation-reduction process
UMP biosynthetic process
response to nutrient
circadian rhythm
uracil metabolic process
response to drug
response to glucocorticoid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support