PA5-27172 targets Dopamine Receptor D1 in IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27172 immunogen is synthetic peptide corresponding to a region within amino acids 347 and 441 of Human Dopamine Receptor D1.
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This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
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Protein Aliases: D(1A) dopamine receptor; D1 receptor; D1A dopamine receptor; DADR; Dopamine D1 receptor; dopamine receptor D1A; DRD1A; G protein-coupled receptor DRD1
Gene Aliases: C030036C15Rik; DADR; Drd-1; DRD1; DRD1A; Gpcr15