In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Rabbit (100%).
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
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Protein Aliases: D(1A) dopamine receptor; DADR; Dopamine D1 receptor; DRD1A
Gene Aliases: DADR; DRD1; DRD1A
UniProt ID: (Human) P21728
Entrez Gene ID: (Human) 1812