Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon, Marmoset (95%) Elephant (90%) Dog, Rabbit (85%) Horse (80%).
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
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Protein Aliases: D(1A) dopamine receptor; D-1 dopamine receptor; D1 dopamine receptor; D1a dopamine receptor; D1a receptor; DADR; Dopamine 1 receptor; Dopamine d-1 receptor; Dopamine D1 receptor; Dopamine d1a receptor; Dopamine receptor D1; Dopamine receptor d1a; Dopamine type 1 receptor; DRD1; DRD1A
Gene Aliases: DADR; DRD1; DRD1A
UniProt ID: (Human) P21728
Entrez Gene ID: (Human) 1812