Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon, Marmoset (95%) Elephant (90%) Dog, Rabbit (85%) Horse (80%).
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D(1A) dopamine receptor; D1a receptor; Dopamine 1 receptor; Dopamine D1 receptor
Gene Aliases: DADR; DRD1; DRD1A
UniProt ID: (Human) P21728
Entrez Gene ID: (Human) 1812
Molecular Function: G-protein coupled receptor