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Invitrogen
DRD1 Polyclonal Antibody
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Product Details
PA5-33477
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 20 amino acid peptide from 2nd extracellular domain of human DRD1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon, Marmoset (95%) Elephant (90%) Dog, Rabbit (85%) Horse (80%).
This antibody is not recommended for use in ICC/IF and IHC (F).
Target Information
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: D(1A) dopamine receptor; D1a receptor; Dopamine 1 receptor; Dopamine D1 receptor; DRD1; G-protein coupled receptor; unnamed protein product
Gene Aliases: D1R; DADR; DRD1; DRD1A
UniProt ID: (Human) P21728
Entrez Gene ID: (Human) 1812
temperature homeostasis
conditioned taste aversion
behavioral fear response
neuron migration
synaptic transmission, dopaminergic
response to amphetamine
protein import into nucleus
muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
dopamine receptor signaling pathway
synapse assembly
learning
memory
mating behavior
grooming behavior
locomotory behavior
adult walking behavior
feeding behavior
associative learning
visual learning
response to xenobiotic stimulus
astrocyte development
dopamine transport
cell migration
transmission of nerve impulse
neuronal action potential
dentate gyrus development
striatum development
hippocampus development
cerebral cortex GABAergic interneuron migration
positive regulation of cell migration
peristalsis
operant conditioning
synaptic transmission, glutamatergic
regulation of dopamine metabolic process
response to cocaine
vasodilation
dopamine metabolic process
maternal behavior
positive regulation of potassium ion transport
positive regulation of MAPK cascade
glucose import
habituation
sensitization
behavioral response to cocaine
positive regulation of release of sequestered calcium ion into cytosol
regulation of dopamine uptake involved in synaptic transmission
positive regulation of synaptic transmission, glutamatergic
prepulse inhibition
phospholipase C-activating dopamine receptor signaling pathway
long-term synaptic potentiation
long term synaptic depression
cellular response to catecholamine stimulus
adenylate cyclase-activating adrenergic receptor signaling pathway
modification of postsynaptic structure
presynaptic modulation of chemical synaptic transmission
positive regulation of neuron migration
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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