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Proteintech
DRD5 Polyclonal Antibody
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Product Details
20310-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DRD5 Fusion Protein Ag14145 (351-477 aa encoded by BC009748)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Amount
22.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NSSLNPVIY AFNADFQKVF AQLLGCSHFC SRTPVETVNI SNELISYNQD IVFHKEIAAA YIHMMPNAVT PGNREVDNDE EEGPFDRMFQ IYQTSPDGDP VAESVWELDC EGEISLDKIT PFTPNGFH (351-477 aa encoded by BC009748)
Target Information
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: D(1B) dopamine receptor; D(5) dopamine receptor; D1b receptor; D1beta dopamine receptor; Dopamine 5 receptor; Dopamine D5 receptor; dopamine receptor 5; dopamine receptor D1B; DRD 1B; DRD 5; Hd5dr; MGC10601; unnamed protein product
Gene Aliases: D1B; D5R; DBDR; Drd-5; DRD1B; DRD1L2; DRD5; Gpcr1
UniProt ID: (Human) P21918, (Mouse) Q8BLD9, (Rat) P25115
Entrez Gene ID: (Human) 1816, (Mouse) 13492, (Rat) 25195
synaptic transmission, dopaminergic
response to amphetamine
regulation of systemic arterial blood pressure by vasopressin
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
cellular calcium ion homeostasis
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
dopamine receptor signaling pathway
chemical synaptic transmission
mating behavior
associative learning
transmission of nerve impulse
negative regulation of NAD(P)H oxidase activity
wound healing
response to cocaine
positive regulation of MAPK cascade
positive regulation of adenylate cyclase activity
negative regulation of blood pressure
regulation of female receptivity
sensitization
phospholipase C-activating dopamine receptor signaling pathway
long term synaptic depression
cellular response to catecholamine stimulus
adenylate cyclase-activating adrenergic receptor signaling pathway
reactive oxygen species metabolic process
negative regulation of protein kinase activity
visual learning
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
negative regulation of cell migration
positive regulation of cAMP biosynthetic process
regulation of long-term neuronal synaptic plasticity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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