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Invitrogen
DSCAM Polyclonal Antibody
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Product Details
PA5-42698
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human DSCAM
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: MRVCNSAGCA EKQANFATLN YDGSTIPPLI KSVVQNEEGL TTNEGLKMLV
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Target Information
This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell adhesion molecule DSCAM; CHD2; Down syndrome cell adhesion molecule; Down syndrome cell adhesion molecule homolog; DSCI1
Gene Aliases: 4932410A21Rik; CHD2; CHD2-42; CHD2-52; DSCAM
UniProt ID: (Human) O60469, (Mouse) Q9ERC8
Entrez Gene ID: (Human) 1826, (Mouse) 13508
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
nervous system development
axon guidance
synapse assembly
central nervous system development
locomotory behavior
retina layer formation
social behavior
synaptic transmission, glutamatergic
netrin-activated signaling pathway
positive regulation of phosphorylation
dendrite morphogenesis
positive regulation of axon extension involved in axon guidance
post-embryonic retina morphogenesis in camera-type eye
camera-type eye photoreceptor cell differentiation
dendritic spine development
dendrite self-avoidance
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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