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Proteintech
DSG2 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-21880
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DSG2 fusion protein Ag16393
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: GELDDRFLD DLGLKFKTLA EVCLGQKIDI NKEIEQRQKP ATETSMNTAS HSLCEQTMVN SENTYSSGSS FPVPKSLQEA NAEKVTQEIV TERSVSSRQA QKVATPLPDP MASRNVIATE TSYVTGSTMP PTTVILGPSQ PQSLIVTERV YAPASTLVDQ PYANEGTVVV TERVIQPHGG GSNPLEGTQH LQDVPYVMVR ERESFLAPSS GVQPTLAMPN IAVGQNVTVT ERVLAPASTL QSSYQIPTEN SMTARNTTVS GAGVPGPLPD FGLEESGHSN STITTSSTRV TKHSTVQHSY S
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARVC10; ARVD10; Cadherin family member 5; CMD1BB; desmoglein 2; Desmoglein-2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037
Gene Aliases: AA408168; CDHF5; D18Ertd293e; DSG2; HDGC
UniProt ID: (Human) Q14126, (Mouse) O55111
Entrez Gene ID: (Human) 1829, (Mouse) 13511, (Rat) 307562
desmosome organization
Purkinje myocyte development
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
response to progesterone
maternal process involved in female pregnancy
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
regulation of ventricular cardiac muscle cell action potential
ventricular cardiac muscle cell action potential
bundle of His cell to Purkinje myocyte communication
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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