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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
DSG4 Fusion Protein Ag19520 (855-1040 aa encoded by BC132907) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.63 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: FPSHQACIP ISTDLPLLGP NYFVNESSGL TPSEVEFQEE MAASEPVVHG DIIVTETYGN ADPCVQPTTI IFDPQLAPNV VVTEAVMAPV YDIQGNICVP AELADYNNVI YAERVLASPG VPDMSNSSTT EGCMGPVMSG NILVGPEIQV MQMMSPDLPI GQTVGSTSPM TSRHRVTRYS NIHYTQQ (855-1040 aa encoded by BC132907)
Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cadherin family member 13; Desmoglein-4; Desmoglein4; lanceolate hair
Gene Aliases: CDGF13; CDHF13; DSG4; HYPT6; LAH
UniProt ID: (Human) Q86SJ6, (Mouse) Q7TMD7
Entrez Gene ID: (Human) 147409, (Mouse) 16769
Molecular Function:
cadherin
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