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Proteintech
DST Polyclonal Antibody
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Product Details
28438-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DST Fusion Protein Ag28833
Conjugate
Form
Liquid
Concentration
367 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; BPA; Bullous pemphigoid antigen 1; bullous pemphigoid antigen 1, isoform 5; bullous pemphigoid antigen 1, isoforms 1/2/3/4; bullous pemphigoid antigen 1, isoforms 6/7; Dystonia musculorum protein; Dystonin; Hemidesmosomal plaque protein; Microtubule actin cross-linking factor 2; trabeculin-beta
Gene Aliases: 2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; BP240; BPA; Bpag; BPAG1; BPAG1-n; CATX-15; CATX15; D6S1101; DMH; DST; DT; EBSB2; HSAN6; KIAA0728; MACF2; mKIAA0728; nmf203; nmf339
UniProt ID: (Human) Q03001, (Mouse) Q91ZU6
Entrez Gene ID: (Human) 667, (Mouse) 13518
actin binding
integrin binding
calcium ion binding
protein binding
protein C-terminus binding
microtubule plus-end binding
microtubule binding
cytoskeletal protein binding
protein homodimerization activity
metal ion binding
intermediate filament binding protein
cytoskeletal protein
intermediate filament
cytoskeleton organization
cell adhesion
integrin-mediated signaling pathway
response to wounding
maintenance of cell polarity
intermediate filament cytoskeleton organization
cell motility
cell cycle arrest
axonogenesis
retrograde axonal transport
regulation of microtubule polymerization or depolymerization
cytoplasmic microtubule organization
intracellular transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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