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Product Details
17480-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DTD1 Fusion Protein Ag11510 (1-209 aa encoded by BC045167)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKAVVQRVT RASVTVGGEQ ISAIGRGICV LLGISLEDTQ KELEHMVRKI LNLRVFEDES GKHWSKSVMD KQYEILCVSQ FTLQCVLKGN KPDFNLAMPT EQAEGFYNSF LEQLRKTYRP ELIKDGKFGA YMQVHIQNDG PVTIELESPA PGTATSDPKQ LSKLEKQQQR KEKTRAKGPS ESSKERNTPR KEDRSASSGA EGDVSSEREP (1-209 aa encoded by BC045167)
Target Information
Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. It is a holoenzyme shell (approximately 450 kDa) consisting of 24 subunits of two types, H (heavy) and L (light), and capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiologic status of the cell, the ratio of H to L subunits in ferritin can vary widely. It can be viewed not only as part of a group of iron regulatory proteins that include transferrin and the transferrin receptor, but also as a member of the protein family that orchestrates the cellular defense against stress and inflammation. Ferritin is found in the liver, spleen, kidney and heart. Only a small amount is found in the blood. The blood level of ferritin serves as an indicator of the amount of iron stored in the body.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bA379J5.3; bA555E18.1; D-aminoacyl-tRNA deacylase 1; D-tyrosyl-tRNA deacylase 1 homolog; D-tyrosyl-tRNA(Tyr) deacylase 1; DNA-unwinding element-binding protein B; DTD; DUE-B; Gly-tRNA(Ala) deacylase; histidyl tRNA synthetase 2; Histidyl-tRNA synthase-related; histidyl-tRNA synthetase 2; MGC119131; MGC41905
Gene Aliases: 0610006H08Rik; C20orf88; DTD1; DUE-B; DUEB; HARS2; pqn-68
UniProt ID: (Human) Q8TEA8, (Mouse) Q9DD18
Entrez Gene ID: (Human) 92675, (Mouse) 66044, (Rat) 362227
aminoacyl-tRNA editing activity
DNA binding
metal ion binding
D-tyrosyl-tRNA(Tyr) deacylase activity
molecular_function
nuclease activity
hydrolase activity
hydrolase activity, acting on ester bonds
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
aminoacyl-tRNA ligase activity
esterase
hydrolase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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