Recommended positive controls: HeLa.
Predicted reactivity: Mouse (98%), Xenopus laevis (86%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
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Protein Aliases: deltex 1; deltex 1, E3 ubiquitin ligase; deltex homolog 1; Deltex1; E3 ubiquitin-protein ligase DTX1; hDTX1; hDx-1; Protein deltex-1; RING-type E3 ubiquitin transferase DTX1
Gene Aliases: DTX1; hDx-1
UniProt ID: (Human) Q86Y01
Entrez Gene ID: (Human) 1840
Molecular Function: ubiquitin-protein ligase