Predicted to react with bovine, mouse and rat based on sequence homology.
Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-terminal domain nuclear envelope phosphatase 1; CTD nuclear envelope phosphatase 1; DULLARD; dullard homolog; Serine/threonine-protein phosphatase dullard
Gene Aliases: CTDNEP1; DULLARD; HSA011916; NET56
UniProt ID: (Human) O95476
Entrez Gene ID: (Human) 23399