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Invitrogen
DUOX2 Polyclonal Antibody
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Product Details
PA5-71497
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
200 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bifunctional oxidase; Dual oxidase 2; dual oxidase-like domains 2; flavoprotein NADPH oxidase; Large NOX 2; Long NOX 2; NADH/NADPH thyroid oxidase p138-tox; NADPH oxidase/peroxidase DUOX2; NADPH thyroid oxidase 2; nicotinamide adenine dinucleotide phosphate oxidase; p138 thyroid oxidase; Thyroid oxidase 2
Gene Aliases: DUOX2; LNOX2; NOXEF2; P138-TOX; TDH6; THOX2
UniProt ID: (Human) Q9NRD8
Entrez Gene ID: (Human) 50506
thyroid hormone generation
defense response
response to oxidative stress
response to virus
cytokine-mediated signaling pathway
cuticle development
hormone biosynthetic process
superoxide anion generation
hydrogen peroxide catabolic process
hydrogen peroxide biosynthetic process
response to cAMP
cellular response to cytokine stimulus
positive regulation of wound healing
cellular oxidant detoxification
positive regulation of cell motility
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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