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Invitrogen
DUSP10 Polyclonal Antibody
FIGURE: 1 / 7
DUSP10 Antibody (PA5-106794) in ICC/IF
Immunocytochemistry analysis of DUSP10 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with DUSP10 polyclonal antibody (Product # PA5-106794) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-106794
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DUSP10(Accession Q9Y6W6), corresponding to amino acid residues H357-H407.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854462
Product Specific Information
Antibody detects endogenous levels of total DUSP10.
Target Information
Microsomal long and very long chain fatty acid elongation uses malonyl-CoA as the 2-carbon donor and consists of 4 sequential reactions. GPSN2 catalyzes the final step, reducing trans-2, 3-enoyl-CoA to saturated acyl-CoA. Microsomal long and very long chain fatty acid elongation uses malonyl-CoA as the 2-carbon donor and consists of 4 sequential reactions. TER catalyzes the final step, reducing trans-2, 3-enoyl-CoA to saturated acyl-CoA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dual specificity phosphatase MKP-5; Dual specificity protein phosphatase 10; MAP kinase phosphatase 5; Mitogen-activated protein kinase phosphatase 5; serine/threonine specific protein phosphatase
Gene Aliases: 2610306G15Rik; AI158871; DUSP10; MKP-5; MKP5
UniProt ID: (Human) Q9Y6W6, (Mouse) Q9ESS0
Entrez Gene ID: (Human) 11221, (Mouse) 63953, (Rat) 63995
inactivation of MAPK activity
regulation of adaptive immune response
protein dephosphorylation
response to stress
JNK cascade
dephosphorylation
response to lipopolysaccharide
peptidyl-tyrosine dephosphorylation
negative regulation of JUN kinase activity
negative regulation of protein kinase activity by regulation of protein phosphorylation
oligodendrocyte differentiation
negative regulation of oligodendrocyte differentiation
negative regulation of respiratory burst involved in inflammatory response
regulation of brown fat cell differentiation
negative regulation of stress-activated MAPK cascade
regulation of innate immune response
negative regulation of JNK cascade
response to organic substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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