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Product Details
PA5-51153
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length fusion protein of human DUSP11
Conjugate
Form
Liquid
Concentration
1.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2636601
Product Specific Information
The antibody detects endogenous levels of total DUSP11 protein.
Target Information
DUSP11 (dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus, and is novel in that it binds directly to RNA and splicing factors, and thus suggested to participate in nuclear mRNA metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dual specificity phosphatase 11 (RNA/RNP complex 1-interacting); Dual specificity protein phosphatase 11; Phosphatase that interacts with RNA/RNP complex 1; RNA/RNP complex 1-interacting; RNA/RNP complex-1-interacting phosphatase; RNA/RNP complex-interacting phosphatase; serine/threonine specific protein phosphatase
Gene Aliases: DUSP11; PIR1
UniProt ID: (Human) O75319
Entrez Gene ID: (Human) 8446
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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