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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 217 of Human DUSP19|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28007 targets DUSP19 in WB applications and shows reactivity with Human samples.
The PA5-28007 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 217 of Human DUSP19.
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dual specificity phosphatase TS-DSP1; dual specificity protein phosphatase 19; DUSP17; LMW-DSP3; LMWDSP3; low molecular weight dual specificity phosphatase 3; protein phosphatase SKRP1; SAPK pathway-regulating phosphatase 1; SKRP1; stress-activated protein kinase pathway-regulating ph; stress-activated protein kinase pathway-regulating phosphatase 1; TS-DSP1
DUSP17; DUSP19; LMWDSP3; SKRP1; TS-DSP1