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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from internal region of human DUSP26.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||6 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Bat, Hamster, Elephant, Panda, Horse (100%).
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DSP-4; dual specificity phosphatase SKRP3; dual specificity protein phosphatase 26; dual-specificity phosphatase SKRP3; DUSP24; LDP-4; low-molecular-mass dual-specificity phosphatase 4; MAP kinase phosphatase 8; mitogen-; mitogen-activated protein kinase phosphatase 8; MKP-8; MKP8; NATA1; neuroendocrine-associated phosphatase; Novel amplified gene in thyroid anaplastic cancer; SKRP3
DSP-4; DUSP24; DUSP26; LDP-4; LDP4; MKP-8; MKP8; NATA1; NEAP; SKRP3