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Invitrogen
DVL3 Polyclonal Antibody
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FIGURE: 1 / 1
DVL3 Antibody (PA5-114375) in WB
Western blot analysis of DVL3 in the following samples: Lane 1: rat brain tissue lysates, Lane 2: mouse brain tissue lysates. Samples consisting of 50 µg (reducing conditions) of protein was separated with 5-20% SDS-PAGE gel (70V, Stacking gel; 90V, Resolving gel; 2-3 hrs.), transferred to a Nitrocellulose membrane (150mA, 50-90 min) and washed with TBS-0.1% Tween (3 times, 5 minutes/wash) and blocked with 5% Non-fat Milk/TBS (1.5 hrs., room temperature). The membrane was incubated in DVL3 polyclonal antibody (Product # PA5-114375) at a di... View More
Product Details
PA5-114375
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Dishevelled 3 (397-434aa DTERLDDFHLSIHSDMAAIVKAMASPESGLEVRDRMW L).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat brain tissue, mouse brain tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila disheveled gene, dsh. The Drosophila disheveled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytoplasmic phosphoprotein; dishevelled 3 (homologous to Drosophila dsh); dishevelled 3, dsh homolog; dishevelled, dsh homolog 3; Dishevelled-3; DSH homolog 3; dvl-3; KIAA0208; OTTHUMP00000210778; Segment polarity protein dishevelled homolog DVL-3; unnamed protein product
Gene Aliases: DRS3; DVL3; KIAA0208
UniProt ID: (Human) Q92997, (Mouse) Q61062
Entrez Gene ID: (Human) 1857, (Mouse) 13544, (Rat) 303811
small GTPase mediated signal transduction
response to xenobiotic stimulus
Wnt signaling pathway
regulation of protein localization
regulation of actin cytoskeleton organization
intracellular signal transduction
non-canonical Wnt signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
protein stabilization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
positive regulation of neuron projection arborization
positive regulation of protein phosphorylation
heart morphogenesis
outflow tract septum morphogenesis
multicellular organism development
non-canonical Wnt signaling pathway via JNK cascade
positive regulation of JUN kinase activity
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
response to drug
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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