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E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
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Protein Aliases: DAZ interacting protein 3, zinc finger; DAZ interacting zinc finger protein 3; DAZ-interacting protein 3; DAZ-interacting protein 3 homolog; E3 ubiquitin-protein ligase DZIP3; hRUL138; human RNA-binding ubiquitin ligase of 138 kDa; protein phosphatase 1, regulatory subunit 66; RING-type E3 ubiquitin transferase DZIP3; RNA-binding RING-H2 protein-ubiquitin ligase; RNA-binding ubiquitin ligase of 138 kDa; UURF2 ubiquitin ligase; zinc finger DAZ interacting protein 3
Gene Aliases: 2310047C04Rik; 2A-HUB; 6430549P11Rik; A230104G20; DZIP3; hRUL138; KIAA0675; PPP1R66; RGD1563278; UURF2
UniProt ID: (Human) Q86Y13, (Mouse) Q7TPV2
Entrez Gene ID: (Human) 9666, (Mouse) 224170, (Rat) 303963
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