|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 192 of Human Decorin|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
PA5-27370 targets Decorin in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27370 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 192 of Human Decorin.
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1.
PA5-27370 was used in immunocytochemistry, immunohistochemistry - paraffin section, and proximity ligation assay characterize the interaction between VAR2CSA and chondroitin sulfate proteoglycans
|Ayres Pereira M,Mandel Clausen T,Pehrson C,Mao Y,Resende M,Daugaard M,Riis Kristensen A,Spliid C,Mathiesen L,E Knudsen L,Damm P,G Theander T,R Hansson S,A Nielsen M,Salanti A||PLoS pathogens (12:null)||2016|