PA5-27370 targets Decorin in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27370 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 192 of Human Decorin.
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The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
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Protein Aliases: Bone proteoglycan II; CSCD; Decorin; decorin proteoglycan; dermatan sulphate proteoglycans II; DSPG2; PG-S2; PG40; PGII; PGS2; proteoglycan core protein; SLRR1B; small leucine-rich protein 1B
Gene Aliases: CSCD; DCN; DSPG2; PG40; PGII; PGS2; SLRR1B
UniProt ID: (Human) P07585
Entrez Gene ID: (Human) 1634