|Immunohistochemistry (Paraffin) (IHC (P))||5-10 µg/ml|
|Western Blot (WB)||1:1000-1:5000|
|Tested Species reactivity||Dog, Hamster, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the C-terminal residues 200-251 of human Derlin-1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris citrate, pH 7-8|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
This antibody is predicted to react with xenopus, bovine, chicken, rat, zebrafish, and mouse based on 100% sequence homology.
Suggested positive control: antigen standard for DERL1 (transient overexpression lysate), KRM (canine microsome) lysates.
Derlin-1 is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate waste disposal sites within the cell.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Degradation in endoplasmic reticulum protein 1; Der1-like domain family, member 1; Der1-like protein 1; derlin 1; Derlin-1; DERtrin-1
Gene Aliases: 1110021N07Rik; AI195141; AW551338; DER-1; DER1; DERL1; Derlin-1; UNQ243/PRO276
Molecular Function: receptor
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