PA5-16705 targets Desmin in IHC (P), IP, and WB applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-16705 immunogen is a synthetic peptide mapping near the C-terminus of human desmin.
PA5-16705 has been successfully used in immunofluorescence and western blotting analysis of Desmin in primary human hepatic stellate cells.
Desmin is an intermediate filament protein of both smooth and striated muscles. Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. Anti-desmin antibody is useful in identification of tumors of myogenic origin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Desmin; intermediate filament protein; mutant desmin p.K241E
Gene Aliases: CSM1; CSM2; DES; LGMD2R