Product References
Primitive Cutaneous (P)erivascular (E)pithelioid (C)ell Tumour (PEComa): A New Case Report of a Rare Cutaneous Tumor.
Genes
Cazzato G,Colagrande A,Lospalluti L,Pacello L,Lettini T,Arezzo F,Loizzi V,Lupo C,Casatta N,Cormio G,Maiorano E,Ingravallo G,Resta L
PA5-16705 was used in Immunohistochemistry to present a new case of cPEComa found on the left thigh of a 53-year-old patient with histopathological, immunohistochemical, and molecular information.
Sun Jun 26 00:00:00 EDT 2022
Young and Undamaged rMSA Improves the Healthspan and Lifespan of Mice.
Biomolecules
Tang J,Ju A,Li B,Zhang S,Gong Y,Ma B,Jiang Y,Liu H,Fu Y,Luo Y
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunohistochemistry
Thu Aug 12 00:00:00 EDT 2021
Microtubules orchestrate local translation to enable cardiac growth.
Nature communications
Scarborough EA,Uchida K,Vogel M,Erlitzki N,Iyer M,Phyo SA,Bogush A,Kehat I,Prosser BL
PA5-16705 was used in Immunocytochemistry to show that microtubules are indispensable for cardiac growth via spatiotemporal control of the translational machinery.
Thu Mar 11 00:00:00 EST 2021
Microtubules orchestrate local translation to enable cardiac growth.
Nature communications
Scarborough EA,Uchida K,Vogel M,Erlitzki N,Iyer M,Phyo SA,Bogush A,Kehat I,Prosser BL
PA5-16705 was used in Immunocytochemistry to show that microtubules are indispensable for cardiac growth via spatiotemporal control of the translational machinery.
Thu Mar 11 00:00:00 EST 2021
μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism.
Current research in physiology
Kinney CJ,O'Neill A,Noland K,Huang W,Muriel J,Lukyanenko V,Kane MA,Ward CW,Collier AF,Roche JA,McLenithan JC,Reed PW,Bloch RJ
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunocytochemistry
Sat Jul 16 00:00:00 EDT 2022
μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism.
Current research in physiology
Kinney CJ,O'Neill A,Noland K,Huang W,Muriel J,Lukyanenko V,Kane MA,Ward CW,Collier AF,Roche JA,McLenithan JC,Reed PW,Bloch RJ
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunocytochemistry
Sat Jul 16 00:00:00 EDT 2022
μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism.
Current research in physiology
Kinney CJ,O'Neill A,Noland K,Huang W,Muriel J,Lukyanenko V,Kane MA,Ward CW,Collier AF,Roche JA,McLenithan JC,Reed PW,Bloch RJ
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunocytochemistry
Sat Jul 16 00:00:00 EDT 2022
Splice modulating antisense oligonucleotides restore some acid-alpha-glucosidase activity in cells derived from patients with late-onset Pompe disease.
Scientific reports
Aung-Htut MT,Ham KA,Tchan M,Johnsen R,Schnell FJ,Fletcher S,Wilton SD
PA5-16705 was used in Western Blotting to identify an oligomer sequence that maximally increased enzyme activity in all fibroblasts.
Tue Apr 21 00:00:00 EDT 2020
Splice modulating antisense oligonucleotides restore some acid-alpha-glucosidase activity in cells derived from patients with late-onset Pompe disease.
Scientific reports
Aung-Htut MT,Ham KA,Tchan M,Johnsen R,Schnell FJ,Fletcher S,Wilton SD
PA5-16705 was used in Western Blotting to identify an oligomer sequence that maximally increased enzyme activity in all fibroblasts.
Tue Apr 21 00:00:00 EDT 2020
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
Molecular neurodegeneration
Frew J,Baradaran-Heravi A,Balgi AD,Wu X,Yan TD,Arns S,Shidmoossavee FS,Tan J,Jaquith JB,Jansen-West KR,Lynn FC,Gao FB,Petrucelli L,Feldman HH,Mackenzie IR,Roberge M,Nygaard HB
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunohistochemistry
Mon Mar 16 00:00:00 EDT 2020
Heterogenetic parabiosis between healthy and dystrophic mice improve the histopathology in muscular dystrophy.
Scientific reports
Lu A,Guo P,Wang L,Tseng C,Huard M,Allen C,McCarrick-Walmsley R,Whitney KE,Huard J
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunocytochemistry
Mon Apr 27 00:00:00 EDT 2020
Heterogenetic parabiosis between healthy and dystrophic mice improve the histopathology in muscular dystrophy.
Scientific reports
Lu A,Guo P,Wang L,Tseng C,Huard M,Allen C,McCarrick-Walmsley R,Whitney KE,Huard J
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunocytochemistry
Mon Apr 27 00:00:00 EDT 2020
Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression.
Scientific reports
Badu-Mensah A,Guo X,McAleer CW,Rumsey JW,Hickman JJ
PA5-16705 was used in Immunocytochemistry-immunoflourescence to present the first well-characterized in vitro iPSC-derived muscle model that demonstrates SOD1 toxicity effects on human muscle regeneration, contractility and metabolic function in amyotrophic lateral sclerosis (ALS).
Mon Aug 31 00:00:00 EDT 2020
Accumulation of myeloid lineage cells is mapping out liver fibrosis post injury: a targetable lesion using Ketanserin.
Experimental & molecular medicine
Amini-Nik S,Sadri AR,Diao L,Belo C,Jeschke MG
PA5-16705 was used in Western Blotting to investigate the role of myeloid lineage cells in the liver following acute injury.
Thu Jul 19 00:00:00 EDT 2018
Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.
The Journal of clinical investigation
Koyama Y,Wang P,Liang S,Iwaisako K,Liu X,Xu J,Zhang M,Sun M,Cong M,Karin D,Taura K,Benner C,Heinz S,Bera T,Brenner DA,Kisseleva T
PA5-16705 was used in Immunohistochemistry to explore the role of mesothelin/mucin 16 signalling in liver fibrosis induced by bile duct ligation.
Mon Apr 03 00:00:00 EDT 2017
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.
Journal of molecular and cellular cardiology
Ackermann MA,Petrosino JM,Manring HR,Wright P,Shettigar V,Kilic A,Janssen PML,Ziolo MT,Accornero F
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunohistochemistry
Wed Nov 01 00:00:00 EDT 2017
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.
Journal of molecular and cellular cardiology
Ackermann MA,Petrosino JM,Manring HR,Wright P,Shettigar V,Kilic A,Janssen PML,Ziolo MT,Accornero F
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunohistochemistry
Wed Nov 01 00:00:00 EDT 2017
Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.
Nature
Hyslop LA,Blakeley P,Craven L,Richardson J,Fogarty NM,Fragouli E,Lamb M,Wamaitha SE,Prathalingam N,Zhang Q,O'Keefe H,Takeda Y,Arizzi L,Alfarawati S,Tuppen HA,Irving L,Kalleas D,Choudhary M,Wells D,Murdoch AP,Turnbull DM,Niakan KK,Herbert M
PA516705 was used in immunohistochemistry to discuss the first preclinical studies on pronuclear transplantation
Thu Jun 16 00:00:00 EDT 2016
Sodium 4-phenylbutyrate reduces myofiber damage in a mouse model of Duchenne muscular dystrophy.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Begam M,Abro VM,Mueller AL,Roche JA
PA516705 was used in immunohistochemistry to test if sodium 4-phenylbutyrate reduces contraction-induced myofiber damage in a mouse model of Duchenne muscular dystrophy
Sat Oct 01 00:00:00 EDT 2016
Tumour resistance in induced pluripotent stem cells derived from naked mole-rats.
Nature communications
Miyawaki S,Kawamura Y,Oiwa Y,Shimizu A,Hachiya T,Bono H,Koya I,Okada Y,Kimura T,Tsuchiya Y,Suzuki S,Onishi N,Kuzumaki N,Matsuzaki Y,Narita M,Ikeda E,Okanoya K,Seino K,Saya H,Okano H,Miura K
PA5-16705 was used in immunocytochemistry to use naked mole-rat-induced pluripotent stem cells to study mechanisms of cancer resistance
Tue May 10 00:00:00 EDT 2016
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
The Journal of clinical investigation
Mu X,Español-Suñer R,Mederacke I,Affò S,Manco R,Sempoux C,Lemaigre FP,Adili A,Yuan D,Weber A,Unger K,Heikenwälder M,Leclercq IA,Schwabe RF
PA5-16705 was used in immunohistochemistry - paraffin section to elucidate the origin of hepatocellular carcinoma.
Thu Oct 01 00:00:00 EDT 2015
Reconstruction of hepatic stellate cell-incorporated liver capillary structures in small hepatocyte tri-culture using microporous membranes.
Journal of tissue engineering and regenerative medicine
Kasuya J,Sudo R,Masuda G,Mitaka T,Ikeda M,Tanishita K
PA5-16705 was used in immunohistochemistry to study the use of a thin, highly porous membrane to reconstruct hepatic stellate cell-incorporated liver capillary structures in an in vitro triculture
Sun Mar 01 00:00:00 EST 2015
Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury.
Hepatology (Baltimore, Md.)
Lua I,James D,Wang J,Wang KS,Asahina K
PA5-16705 was used in immunocytochemistry and immunohistochemistry to study the ability of murine mesodermal mesenchymal cells to differentiate into myofibroblasts but not epithelial cells
Tue Jul 01 00:00:00 EDT 2014
Endothelial-specific Notch blockade inhibits vascular function and tumor growth through an eNOS-dependent mechanism.
Cancer research
Patenaude A,Fuller M,Chang L,Wong F,Paliouras G,Shaw R,Kyle AH,Umlandt P,Baker JH,Diaz E,Tong J,Minchinton AI,Karsan A
PA5-16705 was used in immunohistochemistry to study the role of eNOS in the mechanism by which vascular function and tumor growth are impaired following endothelial-specific inhibition of Notch
Thu May 01 00:00:00 EDT 2014
Diagnostic pitfalls of differentiating desmoplastic small round cell tumor (DSRCT) from Wilms tumor (WT): overlapping morphologic and immunohistochemical features.
The American journal of surgical pathology
Arnold MA,Schoenfield L,Limketkai BN,Arnold CA
PA5-16705 was used in immunohistochemistry to study the difficulty in differentially diagnosing desmoplastic small round cell tumor and Wilms tumor
Mon Sep 01 00:00:00 EDT 2014
Midkine-deficient mice delayed degeneration and regeneration after skeletal muscle injury.
Acta histochemica
Ikutomo M,Sakakima H,Matsuda F,Yoshida Y
PA5-16705 was used in immunohistochemistry to study the mechanisms underlying the retarded degeneration and regeneration observed following skeletal muscle injury in midkine ablated mice
Sat Mar 01 00:00:00 EST 2014
Solitary tumours associated with Jaagsiekte retrovirus in sheep are heterogeneous and contain cells expressing markers identifying progenitor cells in lung repair.
Journal of comparative pathology
De las Heras M,de Martino A,Borobia M,Ortín A,Álvarez R,Borderías L,Giménez-Más JA
PA5-16705 was used in immunohistochemistry to study the heterogeneity and the presence of lung repair progenitor cells in Jaagsiekte retrovirus-associated solitary tumors in sheep
Tue Nov 18 00:00:00 EST 2014
Anti-interleukin-6 receptor antibody (MR16-1) promotes muscle regeneration via modulation of gene expressions in infiltrated macrophages.
Biochimica et biophysica acta
Fujita R,Kawano F,Ohira T,Nakai N,Shibaguchi T,Nishimoto N,Ohira Y
PA5-16705 was used in immunohistochemistry to study the role of altered infiltrated macrophage gene expression in the mechanism by which an anti-IL-6 antibody promotes the regeneration of damaged skeletal muscle
Wed Oct 01 00:00:00 EDT 2014
Netrin-4 promotes mural cell adhesion and recruitment to endothelial cells.
Vascular cell
Lejmi E,Bouras I,Camelo S,Roumieux M,Minet N,Leré-Déan C,Merkulova-Rainon T,Autret G,Vayssettes C,Clement O,Plouët J,Leconte L
PA5-16705 was used in immunohistochemistry to study the recruitment of mural cells to endothelial cells and the role played by Netrin-4
Tue Jan 28 00:00:00 EST 2014
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
Acta neuropathologica
Almeida S,Gascon E,Tran H,Chou HJ,Gendron TF,Degroot S,Tapper AR,Sellier C,Charlet-Berguerand N,Karydas A,Seeley WW,Boxer AL,Petrucelli L,Miller BL,Gao FB
Published figure using Desmin polyclonal antibody (Product # PA5-16705) in Immunofluorescence
Sun Sep 01 00:00:00 EDT 2013
Evidence for a common progenitor of epithelial and mesenchymal components of the liver.
Cell death and differentiation
Conigliaro A,Amicone L,Costa V,De Santis Puzzonia M,Mancone C,Sacchetti B,Cicchini C,Garibaldi F,Brenner DA,Kisseleva T,Bianco P,Tripodi M
PA5-16705 was used in immunohistochemistry to study whether hepatic epithelial and mesenchymal cells derive from a common progenitor
Thu Aug 01 00:00:00 EDT 2013
Citral is renoprotective for focal segmental glomerulosclerosis by inhibiting oxidative stress and apoptosis and activating Nrf2 pathway in mice.
PloS one
Yang SM,Hua KF,Lin YC,Chen A,Chang JM,Kuoping Chao L,Ho CL,Ka SM
PA5-16705 was used in immunohistochemistry to study the roles of Nrf2 pathway activation and reduced levels of oxidative stress and apoptosis in the ability of citral to protect against focal segmental glomerulosclerosis in a murine model
Sun Jun 15 00:00:00 EDT 2014
The impact of KRAS mutations on VEGF-A production and tumour vascular network.
BMC cancer
Figueras A,Arbos MA,Quiles MT,Viñals F,Germà JR,Capellà G
PA5-16705 was used in immunohistochemistry to study the differential effects on the production of VEGF-A and tumor vasculature development of codon 12 and codon 13 KRAS mutations
Mon Mar 18 00:00:00 EDT 2013
Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.
Nature communications
Mederacke I,Hsu CC,Troeger JS,Huebener P,Mu X,Dapito DH,Pradere JP,Schwabe RF
PA5-16705 was used in immunohistochemistry and western blot to use a novel transgenic mouse to study the dominant role of hepatic stellate cells in liver fibrosis in liver disease regardless of its cause
Tue Jul 15 00:00:00 EDT 2014
Analysis of transplanted bone marrow-derived cells in chronic pancreatitis.
Methods in molecular biology (Clifton, N.J.)
Westphalen CB,Marrache F,Wang TC
PA5-16705 was used in immunohistochemistry to study the transplantation of bone marrow-derived cells in a murine model of acute pancreatitis
Wed Jul 03 00:00:00 EDT 2013
Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.
PloS one
Zhang Z,Almeida S,Lu Y,Nishimura AL,Peng L,Sun D,Wu B,Karydas AM,Tartaglia MC,Fong JC,Miller BL,Farese RV,Moore MJ,Shaw CE,Gao FB
PA5-16705 was used in immunocytochemistry to use patient induced pluripotent stem cell-derived neurons to study the decreased miRNA-9 levels in frontotemporal dementia/ALS patients bearing mutations of TDP-43
Tue Jun 17 00:00:00 EDT 2014
Oral administration of recombinant adeno-associated virus-mediated bone morphogenetic protein-7 suppresses CCl(4)-induced hepatic fibrosis in mice.
Molecular therapy : the journal of the American Society of Gene Therapy
Hao ZM,Cai M,Lv YF,Huang YH,Li HH
PA5-16705 was used in immunohistochemistry to study the ability of an orally administered recombinant AAV-BMP-7 virus to protect against experimentally induced hepatic fibrosis in a murine model
Thu Nov 01 00:00:00 EDT 2012
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.
PLoS pathogens
Zeng M,Southern PJ,Reilly CS,Beilman GJ,Chipman JG,Schacker TW,Haase AT
PA5-16705 was used in immunohistochemistry to test if damage to the lymphoid tissue fibroblastic reticular cell network contributes to naive T cell loss during HIV-1 infection
Sun Jan 01 00:00:00 EST 2012
HSCs play a distinct role in different phases of oval cell-mediated liver regeneration.
Cell biochemistry and function
Chen L,Zhang W,Zhou QD,Yang HQ,Liang HF,Zhang BX,Long X,Chen XP
PA5-16705 was used in western blot to study the role of hepatic stellate cells at various time-points during liver regeneration mediated by hepatic oval cells
Mon Oct 01 00:00:00 EDT 2012
Alterations in intermediate filaments expression in disc cells from the rat temporomandibular joint following exposure to continuous compressive force.
Journal of anatomy
Magara J,Nozawa-Inoue K,Suzuki A,Kawano Y,Ono K,Nomura S,Maeda T
PA5-16705 was used in immunohistochemistry to study the effects of continuous compressive force on rat temporomandibular joint disc cell intermediate filaments expression
Fri Jun 01 00:00:00 EDT 2012
Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects.
Cell reports
Almeida S,Zhang Z,Coppola G,Mao W,Futai K,Karydas A,Geschwind MD,Tartaglia MC,Gao F,Gianni D,Sena-Esteves M,Geschwind DH,Miller BL,Farese RV,Gao FB
PA5-16705 was used in immunocytochemistry to study reversible neuronal defects in frontotemporal dementia using induced pluripotent stem cell models
Thu Oct 25 00:00:00 EDT 2012
Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.
Diagnostic pathology
Yin WH,Li J,Chan JK
PA5-16705 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression
Thu Apr 12 00:00:00 EDT 2012
Lactic acid bacteria convert human fibroblasts to multipotent cells.
PloS one
Ohta K,Kawano R,Ito N
PA5-16705 was used in immunocytochemistry to study the ability of gut lactic acid bacteria to generate multipotent cells from human dermal fibroblasts
Wed Jul 17 00:00:00 EDT 2013
Gene expression during normal and FSHD myogenesis.
BMC medical genomics
Tsumagari K,Chang SC,Lacey M,Baribault C,Chittur SV,Sowden J,Tawil R,Crawford GE,Ehrlich M
PA5-16705 was used in immunocytochemistry to study gene expression during normal and facioscapulohumeral muscular dystrophy myogenesis
Tue Sep 27 00:00:00 EDT 2011
