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Bioss
Dppa4 Polyclonal Antibody
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Product Details
BS-13595R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Dppa4, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The DPPA4 gene encodes developmental pluripotency associated 4, a protein that plays a crucial role in maintaining stem cell pluripotency and facilitating early embryonic development. DPPA4 is primarily expressed in pluripotent stem cells, such as embryonic stem cells, where it contributes to the regulation of gene expression and chromatin structure necessary for pluripotency and differentiation. This protein is also involved in the establishment of epigenetic marks that influence developmental pathways, ensuring the proper formation of tissue types during embryogenesis. DPPA4 functions in stem cell renewal and differentiation, impacting cellular processes that are fundamental to early development. Beyond its roles in normal physiology, DPPA4 has been studied in the context of oncology, where its expression is often upregulated in certain cancers, indicating its potential as a biomarker for tumorigenic stem cell-like properties. Research continues to explore DPPA4's mechanisms and interactions to understand its contributions to development and its implications in disease states, particularly in cancer biology and regenerative medicine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmental pluripotency-associated protein 4; ECAT15-1; Embryonic stem cell-associated transcript 15-1 protein; similar to developmental pluripotency associated 4 isoform 1
Gene Aliases: 2410091M23Rik; C76608; DPPA4; ECAT15-1
UniProt ID: (Human) Q7L190, (Mouse) Q8CCG4
Entrez Gene ID: (Human) 55211, (Mouse) 73693, (Rat) 685378
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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