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Proteintech
Drebrin Polyclonal Antibody
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Product Details
25770-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Drebrin Fusion Protein Ag22634 (1-353 aa encoded by BC007567)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGVSFSGH RLELLAAYEE VIREESAADW ALYTYEDGSD DLKLAASGEG GLQELSGHFE NQKVMYGFCS VKDSQAALPK YVLINWVGED VPDARKCACA SHVAKVAEFF QGVDVIVNAS SVEDIDAGAI GQRLSNGLAR LSSPVLHRLR LREDENAEPV GTTYQKTDAA VEMKRINREQ FWEQAKKEEE LRKEEERKKA LDERLRFEQE RMEQERQEQE ERERRYRERE QQIEEHRRKQ QTLEAEEAKR RLKEQSIFGD HRDEEEETHM KKSESEVEEA AAIIAQRPDN PREFFKQQER VASASAGSCD VPSPFNHRPG SHLDSHRRMA PTPIPTRSPS DSSTASTPVA EQIE (1-353 aa encoded by BC007567)
Target Information
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Developmentally-regulated brain protein; DKFZp434D064; Drebrin; drebrin A; drebrin E; drebrin E2; unnamed protein product
Gene Aliases: D0S117E; DBN1; Drba
UniProt ID: (Human) Q16643, (Mouse) Q9QXS6
Entrez Gene ID: (Human) 1627, (Mouse) 56320
in utero embryonic development
actin filament organization
nervous system development
cell communication by chemical coupling
cell communication by electrical coupling
cell differentiation
positive regulation of synaptic plasticity
maintenance of protein location in cell
regulation of neuronal synaptic plasticity
generation of neurons
regulation of dendrite development
positive regulation of dendritic spine morphogenesis
neural precursor cell proliferation
positive regulation of receptor localization to synapse
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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