The antibody is specific to DROSHA. DROSHA/RNASEN has some transcription forms with MW 160 kDa, 151 kDa, 138 kDa, and 90 kDa.
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: drosha, double-stranded RNA-specific endoribonuclease; drosha, ribonuclease type III; ethanol induced 2; MGC115770; nuclear RNase III Drosha; OTTHUMP00000220910; OTTHUMP00000220911; OTTHUMP00000220912; OTTHUMP00000220913; p241; Protein Drosha; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; Ribonuclease 3; Ribonuclease III; ribonuclease III, nuclear; ribonuclease type III, nuclear; RNase III
Gene Aliases: 1110013A17Rik; AI874853; DROSHA; ETOHI2; HSA242976; RANSE3L; RGD1307626; RN3; RNASE3L; RNASEN