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Proteintech
E2F3 Polyclonal Antibody
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Product Details
27615-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E2F3 Fusion Protein Ag26367 (54-155 aa encoded by NM_001243076)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPGAYIQIL TTNTSTTSCS SSLQSGAVAA GPLLPSAPGA EQTAGSLLYT TPHGPSSRAG LLQQPPALGR GGSGGGGGPP AKRRLELGES GHQYLSDGLK TPKG (54-155 aa encoded by NM _001243076 )
Target Information
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp686C18211; E2F-3; MGC104598; RP1-177P22.2; Transcription factor E2F3
Gene Aliases: E2F-3; E2F3; KIAA0075
UniProt ID: (Human) O00716
Entrez Gene ID: (Human) 1871
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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