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Invitrogen
EAP2 Polyclonal Antibody
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Product Details
PA5-116085
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human TDP2(Accession O95551), corresponding to amino acid residues R321-L362.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total TTRAP.
Target Information
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-Tyr-DNA phosphodiesterase; 5'-tyrosyl-DNA phosphodiesterase; EAP2; EAPII; epididymis secretory sperm binding protein; ETS1-associated protein 2; ETS1-associated protein II; MGC111021; MGC9099; RP1-30M3.3; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; Tyr-DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; Tyrosyl-RNA phosphodiesterase; unnamed protein product; VPg unlinkase
Gene Aliases: AD-022; AD022; D13Ertd656e; dJ30M3.3; EAP2; EAPII; hTDP2; TDP2; TTRAP
UniProt ID: (Human) O95551, (Mouse) Q9JJX7, (Rat) Q3T1H5
Entrez Gene ID: (Human) 51567, (Mouse) 56196, (Rat) 498749
magnesium ion binding
DNA binding
single-stranded DNA binding
transcription corepressor activity
catalytic activity
nuclease activity
protein binding
hydrolase activity
manganese ion binding
tyrosyl-RNA phosphodiesterase activity
metal ion binding
tyrosyl-DNA phosphodiesterase activity
5'-tyrosyl-DNA phosphodiesterase activity
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
photoreceptor cyclic-nucleotide phosphodiesterase activity
endonuclease activity
phosphoric diester hydrolase activity
7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity
inositol phosphosphingolipid phospholipase activity
inositol phosphorylceramide phospholipase activity
mannosyl-inositol phosphorylceramide phospholipase activity
mannosyl-diinositol phosphorylceramide phospholipase activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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