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Product Details
PA5-84410
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SNF8. Recombinant protein control fragment (Product #RP-93343).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791562
Product Specific Information
Immunogen sequence: WSEMLGVGDF YYELGVQIIE VCLALKHRNG GLITLEELHQ QVLKGRGKFA QDVSQDDLIR AIKKLKALGT GFGIIPVGGT YL
Target Information
ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EAP30 subunit of ELL complex; ELL-associated protein of 30 kDa; ESCRT-II complex subunit VPS22; hVps22; SNF8, ESCRT-II complex subunit, homolog; Vacuolar-sorting protein SNF8
Gene Aliases: Dot3; EAP30; SNF8; VPS22
UniProt ID: (Human) Q96H20
Entrez Gene ID: (Human) 11267
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
autophagy
positive regulation of gene expression
regulation of multivesicular body size involved in endosome transport
endosomal transport
endocytic recycling
multivesicular body assembly
regulation of protein catabolic process
protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
regulation of MAP kinase activity
early endosome to late endosome transport
positive regulation of protein catabolic process
regulation of protein complex stability
multivesicular body sorting pathway
positive regulation of exosomal secretion
regulation of viral budding via host ESCRT complex
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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