Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Immunogen sequence: ASGANFEYII AEKRGKNNTV GLIQLNRPKA LNALCDGLID ELNQALKTFE EDPAVGAIVL TGGDKAFAAG ADIKEMQNLS FQDCYSSKFL KHWDHLTQVK KPVIAAVNGY AFGGGCELAM MCDIIYAGEK AQFAQPEILI GTIPGAGGTQ RLTRAVGKSL AMEMVLTGDR ISAQDAKQAG LVSKICPVET LVEEAIQCAE KIASNSKIVV AMAKESVNAA FEMTLTEGSK LEKKLFYSTF ATDDRKEGMT AFVEKRKANF KDQ; Positive Samples: LO2, 293T, U-87MG, MCF7, 22Rv1, Mouse liver, Mouse kidney, Mouse heart, Rat liver; Cellular Location: Mitochondrion matrix
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: enoyl CoA hydratase, short chain, 1, mitochondrial; enoyl Coenzyme A hydratase, short chain 1; enoyl Coenzyme A hydratase, short chain, 1, mitochondrial; Enoyl-CoA hydratase 1; Enoyl-CoA hydratase short chain 1 mitochondrial; Enoyl-CoA hydratase, mitochondrial; Enoyl-CoA hydratase, short chain 1, mitochondrial; enoyl-CoA hydratase, short chain, 1, mitochondrial; mitochondrial short-chain enoyl-coenzyme A hydratase 1; SCEH; short chain enoyl-CoA hydratase; Short-chain enoyl-CoA hydratase
Gene Aliases: C80529; ECHS1; ECHS1D; SCEH
UniProt ID: (Human) P30084, (Rat) P14604, (Mouse) Q8BH95
Entrez Gene ID: (Human) 1892, (Rat) 140547, (Mouse) 93747
Molecular Function:
acetyltransferase
acyltransferase
dehydrogenase
epimerase/racemase
hydratase
isomerase
ligase
lyase
oxidoreductase
transferase
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support
