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Immunogen sequence: SQPTMTQTSS SQGGLGGLSL TTEPVSSNPG YIPSSEANRP SHLSSTGT
Highest antigen sequence indentity to the following orthologs: Rat - 37%, Mouse - 40%.
The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis regulator through modulating IAP expression; ARIA; Endothelial cell-specific chemotaxis regulator; Endothelial cell-specific molecule 2
Gene Aliases: ARIA; ECSCR; ECSM2
UniProt ID: (Human) Q19T08
Entrez Gene ID: (Human) 641700
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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