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Proteintech
ECT2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
26557-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ECT2 fusion protein Ag24836
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
75 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAENSVLTST TGRTSLADSS IFDSKVTEIS KENLLIGSTS YVEEEMPQIE TRVILVQEAG KQEELIKALK DIKVGFVKME SVEEFEGLDS PEFENVFVVT DFQDSVFNDL YKADCRVIGP PVVLNCSQKG EPLPFSCRPL YCTSMMNLVL CFTGFRKKEE LVRLVTLVHH MGGVIRKDFN SKVTHLVANC TQGEKFRVAV SLGTPIMKPE WIYKAWERRN EQDFYAAVDD FRNEFKVPPF QDCILSFLGF SDEEKTNMEE MTEMQGGKYL PLGDERCTHL VVEENIVKDL PFEPSKKLYV VKQEWFWGSI QMDARAGETM YLYEKANTPE LKKSVSMLSL NTPNSNRKRR
Target Information
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epithelial cell-transforming sequence 2 oncogene; FLJ10461; guanine nucleotide exchange factor for Rho GTPases; MGC138291; Rho guanyl-nucleotide exchange factor; ECT2B; unnamed protein product
Gene Aliases: ARHGEF31
UniProt ID: (Human) Q9H8V3
Entrez Gene ID: (Human) 1894
mitotic cytokinesis
nervous system development
activation of protein kinase activity
positive regulation of cytokinesis
intracellular signal transduction
positive regulation of protein import into nucleus
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of GTPase activity
positive regulation of neuron differentiation
regulation of protein kinase activity
regulation of small GTPase mediated signal transduction
protein homooligomerization
regulation of attachment of spindle microtubules to kinetochore
cellular response to hydrogen peroxide
bicellular tight junction assembly
cellular response to calcium ion
cellular response to ionizing radiation
activation of GTPase activity
positive regulation of mitotic cytokinetic process
regulation of cytokinesis, actomyosin contractile ring assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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