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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the C-terminal of EDG2 receptor.|
|Purification||Ammonium sulfate precipitation|
|Contains||0.08% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Lysophosphatidic acid receptor 1 (LPA1, EDG2, VZG-1) is a seven transmembrane receptor coupled to G proteins and has high affinity to lypophosphatidic acid (LPA). LPA1 is a member of the EDG-family of receptors which includes LPA1, LPA2 and LPA3. These receptors mediate the serum borne lipid mediator LPA for a variety biological functions. The activation of LPA1 by LPA has shown to stimulate cell spreading and motility, mitogenesis, and various other nervous system activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
EDG2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; LPA receptor 1; LPA-1; LPA1; lysophosphatidic acid receptor Edg-2; ventricular zone gene 1
edg-2; EDG2; Gpcr26; GPR26; LPA1; LPAR1; Mrec1.3; rec.1.3; vzg-1; VZG1