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EDG2 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis.
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Protein Aliases: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; LPA receptor 1; LPA-1; Lysophosphatidic acid receptor 1; Lysophosphatidic acid receptor Edg-2; ventricular zone gene 1
Gene Aliases: edg-2; EDG2; Gpcr26; Gpcr91; GPR26; LPA1; LPAR1; Mrec1.3; rec.1.3; vzg-1; VZG1
Molecular Function: G-protein coupled receptor