Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.^M
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This affinity purified antibody is directed against human EEF1A1. This product is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above. A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to EEF1A1 human, mouse, rat, bovine, rabbit, cat, horse, Chinese hamster, Gallus gallus, Pan troglodytes, and Pongoabelii. May have cross-reactivity to EEF1A to Danio rerio; and eef1as to Xenopuslaevis.
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cervical cancer suppressor 3; CTCL tumor antigen; eEF1A-1; EF-1-alpha-1; EF-Tu; EF1a-like protein; EF1A1; elongation factor 1 alpha subunit; Elongation factor 1-alpha 1; Elongation factor Tu; Eukaryotic elongation factor 1 A-1; eukaryotic translation elongation factor 1 alpha 1-like 14; glucocorticoid receptor AF-1 specific elongation factor; GRAF 1EF; leukocyte receptor cluster (LRC) member 7; Leukocyte receptor cluster member 7; prostate tumor-inducing protein 1; translation elongation factor 1 alpha 1-like 14
Gene Aliases: CCS-3; CCS3; EE1A1; EEF-1; EEF1A; eEF1A-1; EEF1A1; EF-Tu; EF1A; GRAF-1EF; HNGC:16303; LENG7; PTI1
UniProt ID: (Human) P68104
Entrez Gene ID: (Human) 1915
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