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Invitrogen
EEF1D Polyclonal Antibody
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Product Details
PA5-96147
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human EEF1D (NP_0011235291)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
21 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MATNFLAHEK IWFDKFKYDD AERRFYEQMN GPVAGASRQE NGASVILRDI ARARENIQKS LAGSSGPGAS SGTSGDHGEL VVRIASLEVE NQSLRGVVQE LQQAISKLEA RLNVLEKSSP GHRATAPQTQ HVSPMRQVEP PAKKPATPAE DDEDDDIDLF; Positive Samples: SH-SY5Y, PC-3, BT-474, Jurkat, A-549, Mouse spleen; Cellular Location: Nucleus
Target Information
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Antigen NY-CO-4; EEF 1D; EF 1 delta; EF 1D; EF-1-delta; Elongation factor 1-delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); guanine nucleotide exchange protein; translation elongation factor 1-delta subunit; unnamed protein product
Gene Aliases: EEF1D; EF-1-delta; EF-1D; EF1D; FP1047; NEDTCHAL
UniProt ID: (Human) P29692, (Mouse) P57776, (Rat) Q68FR9
Entrez Gene ID: (Human) 1936, (Mouse) 66656, (Rat) 300033
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
translation elongation factor activity
guanyl-nucleotide exchange factor activity
protein binding
translation factor activity, RNA binding
heat shock protein binding
cadherin binding
DNA-binding transcription factor binding
signal transducer activity
activating transcription factor binding
translation elongation factor
cytoplasmic translational elongation
translation
translational elongation
cellular response to heat
positive regulation of transcription from RNA polymerase II promoter
cellular response to ionizing radiation
transcription, DNA-templated
regulation of transcription, DNA-templated
signal transduction
mRNA transcription
regulation of cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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