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Invitrogen
EFCAB4A Polyclonal Antibody
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Product Details
PA5-61187
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EFCAB4A. Recombinant protein control fragment (Product #RP-97506).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LEAVFESLDQ AHTGFLTARE FCLGLGMFVG VASAQGANPC RTPEETFESG GLDVQGTAGS LDEE
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.
Target Information
EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B; Calcium release-activated calcium channel regulator 2B; Calcium release-activated channel regulator 2B; CRAC channel regulator 2B; CRAC regulator 2B; CRACR2B; EF-hand calcium binding domain 4A; EF-hand calcium-binding domain-containing protein 4A; unnamed protein product
Gene Aliases: CRACR2B; EFCAB4A
UniProt ID: (Human) Q8N4Y2
Entrez Gene ID: (Human) 283229
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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